Pyrogenic Specificity of Streptococcal Exotoxins, Staphylococcal Enterotoxin, and Gram-Negative Endotoxin
AUTOR(ES)
Brunson, K. W.
RESUMO
Streptococcal exotoxin and staphylococcal enterotoxin share several biological properties, including pyrogenicity, lymphocyte mitogenicity, and enhancement of gram-negative endotoxin lethality. These analogies of the toxins prompted comparative pyrogenic studies. When American Dutch rabbits were immunized by repeated intravenous injections of small amounts of staphylococcal enterotoxin, they exhibited a decreased febrile response upon challenge when compared with control animals not previously injected. The same animals responded similarly to control groups when challenged with streptococcal exotoxin A, B, or C. No cross-reactivity was observed in reciprocal cross-tests, using animals immune to the streptococcal toxins and challenging with staphylococcal enterotoxin. No cross-reactivity between either the streptococcal or staphylococcal toxins and bacterial endotoxin was observed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=415003Documentos Relacionados
- Gram-negative Bacterial Infections and Mode of Endotoxin Actions
- Levels of gram-negative bacteria, Aspergillus fumigatus, dust, and endotoxin at compost plants.
- Rapid diagnosis of gram-negative bacterial meningitis by the Limulus endotoxin assay.
- Rapid Detection of Gram-Negative Bacteriuria by Use of the Limulus Endotoxin Assay
- Removal of Endotoxin during Purification of Poly(3-Hydroxybutyrate) from Gram-Negative Bacteria