Rat prostatic binding protein: the complete sequence of the C2 gene and its flanking regions.
AUTOR(ES)
Delaey, B
RESUMO
The complete sequence (2879 bp) of the androgen-controlled rat prostatic binding protein C2 gene and 1023 bp of the 5'- and 2127 bp of the 3'-flanking regions have been determined. The gene contains three exons (93, 203 and 147 bp) and two introns (1630 and 806 bp). It is flanked by two homopurine-homopyrimidine stretches of 55 and 131 nucleotides respectively, located at positions -405 and 4151. These sequences are remarkably sensitive towards S1-nuclease, indicating an altered DNA conformation under superhelical stress. Several palindromes and dyad structures are observed in the 5'-upstream region of the gene and at position -457, and 80% homology to the consensus sequence of a glucocorticoid receptor binding site is found.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=340571Documentos Relacionados
- Prostatic steroid binding protein: organisation of C1 and C2 genes.
- Vitellogenin in Drosophila melanogaster: sequence of the yolk protein I gene and its flanking regions.
- Rat prostatic steroid binding protein: DNA sequence and transcript maps of the two C3 genes.
- Nucleotide sequence of the spinach chloroplast tRNA(CAALeu) gene and its flanking regions.
- Sequence analysis of the Streptococcus mutans fructosyltransferase gene and flanking regions.