Regulation of expression of major outer surface proteins in Borrelia burgdorferi.
AUTOR(ES)
Margolis, N
RESUMO
We have characterized a Borrelia burgdorferi clone (CA-11 2A) that does not synthesize the major outer surface proteins, OspA and OspB. While the osp operon is intact and capable of expression, no mRNA transcript is detectable in this clone. These results suggest that osp operon expression in the B. burgdorferi clone can be regulated at the level of transcription.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=280824Documentos Relacionados
- Virulent strain associated outer membrane proteins of Borrelia burgdorferi.
- Identification of an immunologically important hypervariable domain of major outer surface protein A of Borrelia burgdorferi.
- Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi.
- Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi.
- Mapping antibody-binding domains of the major outer surface membrane protein (OspA) of Borrelia burgdorferi.