Relative Avidities of Human Immunoglobulin G Antibodies for Streptococcal Pyrogenic Exotoxins A and B
AUTOR(ES)
Mascini, Ellen M.
FONTE
American Society for Microbiology
RESUMO
In this pilot study, we investigated the relative avidities for streptococcal pyrogenic exotoxin A (SPE-A) and SPE-B of antibodies in sera from patients with fatal streptococcal toxic shock-like syndrome and from healthy individuals and in intravenous immunoglobulin (IVIG) preparations. We observed a great variation in the relative avidities of patient, control, and IVIG immunoglobulin G (IgG) (values estimated to be between 10−7 and 10−11 M), with mean values for patient IgG about 10-fold lower than those of control IgG.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=95808Documentos Relacionados
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