Relative potency of virulent versus avirulent Legionella pneumophila for induction of cell-mediated immunity.
AUTOR(ES)
Klein, T W
RESUMO
Guinea pigs were infected with either high-passage, low-virulence Legionella pneumophila or low-passage, high-virulence organisms. On an infectious dosage basis, the high-virulence organisms were much more effective at sensitizing animals for positive skin test responses and splenic lymphocyte proliferation responses to homologous antigens. These results suggest that exposure to low doses of virulent L. pneumophila can effectively prime animals for cell-mediated immune responses.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=263693Documentos Relacionados
- Vaccines and cell-mediated immunity.
- Immunity to pathogenic free-living amoebae: role of cell-mediated immunity.
- Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity.
- Influenza in ferrets and guinea pigs: effect on cell-mediated immunity.
- Clinical and immunological associations in myasthenia gravis. 2. Cell-mediated immunity.
