Reliable in vivo model for latent herpes simplex virus reactivation with peripheral virus shedding.
AUTOR(ES)
Nesburn, A B
RESUMO
A long-sought laboratory model, a reliable system for in vivo reactivization of latent herpes simplex infection with peripheral shedding of active virus, is present. Results demonstrate that surgical stimulation of latently infected rabbit trigeminal ganglia induces peripheral release of infectious herpes simplex virus. Virus could be cultured from the tear film in 83% of the stimulated animals' eyes within 48 h.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=421438Documentos Relacionados
- In vivo reactivation of herpes simplex virus in rabbit trigeminal ganglia: electrode model.
- Encephalitis resulting from reactivation of latent herpes simplex virus in mice.
- Reactivation of latent Herpes simplex virus after pneumococcal pneumonia in mice.
- Herpes simplex virus infection in guinea pigs: an animal model for studying latent and recurrent herpes simplex virus infection.
- Social stress and the reactivation of latent herpes simplex virus type 1