Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.
AUTOR(ES)
Furuichi, Y
RESUMO
Reovirus mRNA synthesized in vitro by the virus-associated RNA polymerase in the presence of S-adenosylmethionine contains blocked, methylated 5'-termini with the structure, m-7G(5')ppp(5')G-MpCp. The functional significance and possible mechanism of formation of this novel 5'-5' terminal nucleotide linkage are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=432305Documentos Relacionados
- Reovirus messenger RNA contains a methylated, blocked 5′-terminal structure: m7G(5′)ppp(5′)GmpCp-
- 5'-Terminal m-7G(5')ppp(5')G-m-p in vivo: identification in reovirus genome RNA.
- 5′-Terminus of Moloney Murine Leukemia Virus 35S RNA Is m7G5′ ppp5′ GmpCp
- Chemical synthesis of the 5'-terminal part bearing cap structure of messenger RNA of cytoplasmic polyhedrosis virus (CPV): m7G5'pppAmpG and m7G5'pppAmpGpU.
- m7G5'ppp5'GmptcpUp at the 5' terminus of reovirus messenger RNA.