Replication-defective ecotropic murine leukemia viruses: Detection and quantitation of infectivity using helper-dependent XC plaque formation.
AUTOR(ES)
Rein, A
RESUMO
Clones 8A and NP-N, which appear to be infected with replication-defective variants of murine leukemia virus, produce particles which do not form plques in the XC test. These particles formed XC plaques when amphotropic murine leukemia virus, which is XC negative, was added to the assay plates. This phenomenon can be used as a quantitiative infectivity assay for these replication-defective murine leukemia viruses.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=354312Documentos Relacionados
- Rescue and Transmission of a Replication-Defective Variant of Moloney Murine Leukemia Virus
- A replication-defective variant of Moloney murine leukemia virus. I. Biological characterization.
- Characterization of endonuclease activities in Moloney murine leukemia virus and its replication-defective mutants.
- Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter.
- 5'-terminal nucleotide sequences of mammalian type C helper viruses are conserved in the genomes of replication-defective mammalian transforming viruses.