Resistance to Bacitracin as Modulated by an Escherichia coli Homologue of the Bacitracin ABC Transporter BcrC Subunit from Bacillus licheniformis

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

A small open reading frame from the Escherichia coli chromosome, bcrCEC, encodes a homologue to the BcrC subunit of the bacitracin permease from Bacillus licheniformis. We show that disruption of the chromosomal bcrCEC gene causes bacitracin sensitivity and, conversely, that BcrCEC confers bacitracin resistance when expressed from a multicopy plasmid.

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