Retroviral Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus
AUTOR(ES)
Miletic, Hrvoje
FONTE
American Society for Microbiology
RESUMO
Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=112677Documentos Relacionados
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