Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis
AUTOR(ES)
Manriquez, Juan, Giesen, Laura, Puerto, Constanza del, Gonzalez, Sergio
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2016-08
RESUMO
Abstract: A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consistent with rheumatoid neutrophilic dermatosis (RND). After 3 days of prednisone treatment, the skin eruption resolved. RND is a rare cutaneous manifestation of seropositive RA, characterized by asymptomatic, symmetrical erythematous plaques with a pseudo-vesicular appearance. Histology characteristically reveals a dense, neutrophilic infiltrate with leucocitoclasis but without other signs of vasculitis. Lesions may resolve spontaneously or with RA treatment. This case illustrates an uncommon skin manifestation of active rheumatoid arthritis.
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