Risco para cancer de mama segundo os modelos de Gail, Claus e a propria impressão de mulheres com historia familiar de primeiro grau para cancer mamario

AUTOR(ES)

Wellerson de Aguiar Miranda

DATA DE PUBLICAÇÃO

2004

RESUMO

Objective: To correlate the breast cancer risk according to the GAIL and CLAUS models and the own impression of women with first-degree relatives to this illness. In addition to evaluate the medical interest in detecting the high-risk women to breast cancer, to evaluate the opinion of these women about hormone replacement therapy, the self-breast examination and if they have been undergone to mammograms. Subjects and methods: It was done a cross sectional study to evaluate relatives of women with breast cancer diagnosis and already followed in the Caism-Unicamp at the breast unit. The researcher interviewed the admitted women and data used in the GAIL and CLAUS models were collected. Questions about their own impression of the risk about breast cancer, their opinion about HRT, mammograms and medical aid about investigating their risks. To study the relations among categorical variables and GAIL model data the Fisher exact test was used, and to evaluate the relations among the imaginary risk the qui-square test with Yates correction was used. To correlate the risk models it was used the Spearman correlating index. Results: Twelve per cent of the women are high risk to developing breast cancer according to the GAIL model. No correlations among the GAIL and CLAUS models were observed (r=0.03) neither the own impression: 86% that thought being in high risk were according to GAIL model in moderate risk, and 20% that thought in low risk were in high risk, according to GAIL model (p=0,58). Sixty two per cent of the high risk group, according to GAIL model agree that HRT is unsafe. Eight five per cent of the high risk group had done mammograms and 50% of the moderate risk group, both according to GAIL model, had never done mammograms before (p=0.03). Twenty three per cent of the high risk group and 53% of the moderate group, according to GAIL model, were never asked about their family history in breast cancer matters. Conclusions: About twelve per cent of the women were considered high risk according to GAIL model. The risk values based on the GAIL and CLAUS models and the imaginary risk were not correlated. The women were not safe about using HRT, they did the self-breast examination e half of them have done mammograms. Half of this population refered that have never been asked by their family breast cancer history by a physician before

ASSUNTO(S)

cancer

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