Robustness of the no-interference model for ordering genetic markers.
AUTOR(ES)
Speed, T P
RESUMO
Under the assumption of no chromatid interference, we derive constraints on the probabilities of the different recombination patterns among m + 1 genetic loci. An application of these constraints is a proof that the ordering of the loci that maximizes the likelihood under the assumption of no interference is, in fact, a consistent estimator of the true order even when there is interference.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=48812Documentos Relacionados
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