Role of Eosinophils in the Pathogenesis of Mycobacterium bovis BCG Infection in Gamma Interferon Receptor-Deficient Mice
AUTOR(ES)
Kirman, Joanna
FONTE
American Society for Microbiology
RESUMO
A profound eosinophil infiltration of granulomas is observed in the lungs of Mycobacterium bovis bacillus Calmette Guérin-infected gamma interferon receptor-deficient mice. Blockade of eosinophil proliferation and recruitment into the lung by treatment with anti-interleukin-5 monoclonal antibody marginally reduced mycobacterial growth within the lung but did not affect dissemination of the infection to other tissues.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97512Documentos Relacionados
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