Role of L-threonine dehydrogenase in the catabolism of threonine and synthesis of glycine by Escherichia coli.

AUTOR(ES)

Newman, E B

RESUMO

The enzyme L-threonine dehydrogenase was demonstrated in extracts of Escherichia coli K-12, and was shown to be the first enzyme of the pathway converting threonine to glycine. The enzyme was induced by L-leucine, but not by its substrate, L-threonine. The metabolic significance of leucine as a catabolic signal for amino acid degradation is considered.

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