Role of natural killer cells in infection with the mouse pneumonitis agent (murine Chlamydia trachomatis).
AUTOR(ES)
Williams, D M
RESUMO
Natural killer (NK) activity is increased in both spleen and lung early in pulmonary infection by murine Chlamydia trachomatis in both susceptible nude and resistant heterozygous (nu/+) mice. Ablation of the rise in NK activity by giving the mice antiasialo GM-1 antibody or stimulation of NK activity by immunomodulators did not affect quantitative tissue counts of the mouse pneumonitis biovar of C. trachomatis or significantly affect survival. Studies are needed to further define the role of NK cells in host defense, immunoregulation, and immunopathology during chlamydial infection.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260306Documentos Relacionados
- Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis).
- Immune response in mice infected in the genital tract with mouse pneumonitis agent (Chlamydia trachomatis biovar).
- Role of gamma-delta T cells in murine Chlamydia trachomatis infection.
- Murine Models of Chlamydia trachomatis Genital Tract Infection: Use of Mouse Pneumonitis Strain versus Human Strains
- Analysis of the immune response in mice following intrauterine infection with the Chlamydia trachomatis mouse pneumonitis biovar.
