rpoB Mutations in Streptococcus mitis Clinical Isolates Resistant to Rifampin

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

Activity of rifampin against 129 Streptococcus mitis isolates obtained from patients with hematologic cancer was investigated. One hundred twenty-five strains were susceptible to rifampin, and 4 were resistant (MIC = 32 to 64 μg/ml). Resistance to rifampin was related to mutations in the rpoB gene: His526Asn in three strains and His526Asp in one strain.

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