Sarcoma of breast, with particular reference to its origin from fibroadenoma

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RESUMO

Thirty-nine sarcomas of breast are described. The patients' ages ranged from 26 to 78 years but most patients were middle-aged or elderly. Evidence is adduced that 16 of the tumours arose from pre-existing fibroadenomas and others very probably did so. Many tumours were adenosarcomas and one was a carcinosarcoma which preserved its structure in a lymph-node metastasis. Recurrences were mostly local, but a small group had a much graver prognosis. A pleomorphic and giant-cell structure usually meant a high degree of malignancy but the significance of cartilaginous or bony metaplasia, present in seven tumours, was less certain.

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