Scedosporium apiospermum Soft Tissue Infection Successfully Treated with Voriconazole: Potential Pitfalls in the Transition from Intravenous to Oral Therapy

AUTOR(ES)

Schaenman, Joanna M.

FONTE

American Society for Microbiology

RESUMO

An immunocompromised patient with an invasive soft tissue infection due to Scedosporium apiospermum was successfully treated with voriconazole and surgical debridement. After transition from intravenous to oral therapy, successive adjustments of the oral dose were required to achieve complete resolution. For soft tissue infections due to molds characterized by thin, septate hyphae branching at acute angles, voriconazole should be considered a first-line antifungal agent. The potential usefulness of plasma voriconazole levels for guiding optimal therapy should be investigated.

Documentos Relacionados

• Keratitis Caused by Scedosporium apiospermum Successfully Treated with a Cornea Transplant and Voriconazole
• Use of Voriconazole in Treatment of Scedosporium apiospermum Infection: Case Report
• Cutaneous Scedosporium apiospermum infection in an immunocompromised patient.
• Correlation between In Vitro Susceptibility of Scedosporium apiospermum to Voriconazole and In Vivo Outcome of Scedosporiosis in Guinea Pigs
• Amphotericin B responsive Scedosporium apiospermum infection in a patient with acute myeloid leukaemia.