Sem título traduzido / Avaliação dos efeitos do ultra-som pulsado de baixa intensidade e da atividade física na musculatura esquelética de ratos submetidos ao alcoolismo crônico e posterior lesão por impacto padronizada

AUTOR(ES)

Talita Andrea Bordini Malaman

DATA DE PUBLICAÇÃO

2006

RESUMO

The skeletal muscle tissue is among the organism tissues one of the most affected by the abuse alcohol. The aim of this study was quantify the effects of chronic alcoholism on skeletal muscle of rats submitted or not to exercise training model, as well evaluate the muscle regeneration after mechanism of acute muscular injury, in the gastrocnemius muscle, through a direct non-invasive trauma subsequently associated with a treatment of 3 days with low intensity pulsed ultrasound (USP). For that, it was used twenty male wistar rats were allocated into 4 experimental groups: group I alcoholic without practice exercise training affected by an impact and stimulated with USP, group II control without practice exercise training affected by an impact and stimulated with USP, group III alcoholic with practice exercise training affected by an impact and stimulated with USP and group IV control with practice exercise training affected by an impact and stimulated with USP. All groups suffered muscular injury and stimulation with USP. After this period, the animals were killed. The right gastrocnemius and soleus were collected for detail quantitative histomorphometry and the left gastrocnemius muscle was removed for histology analysis of muscle regeneration. Ours results suggest that fiber muscle recuperation of the alcoholic rats evaluated histopathology, show deeper damaged signs that control rats fibers in the same condition. And ours diagram of chronic alcolism was not effective in the induce chronic alcoholic myopathy.

ASSUNTO(S)

exercise training ultrasound lesão muscular experimental treinamento físico experimental muscle injury ultra-som alcoholic alcoolismo

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