Serodiagnosis of acute hepatitis B virus infection by a modified competitive binding radioimmunoassay.
AUTOR(ES)
Schable, C A
RESUMO
Using the Staphylococcus aureus absorption method, we have modified a commercial radioimmunoassay kit for the determination of total antibody to hepatitis B core antigen so that we can now determine the predominant globulin species of that antibody. One-hundred percent of acute hepatitis B sera had a predominance of immunoglobulin M antibody to hepatitis B core antigen, whereas immunoglobulin G antibody to hepatitis B core antigen was predominant in 98.2% of chronic hepatitis B surface antigen carriers. With this test and the commercially available tests for immunoglobulin M anti-hepatitis A virus, one can now reasonably differentiate acute hepatitis B from non A/non B hepatitis in a chronic hepatitis B surface antigen carrier.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=272515Documentos Relacionados
- Serodiagnosis of viral hepatitis A by a modified competitive binding radioimmunoassay for immunoglobulin M anti-hepatitis A virus.
- Serodiagnosis of viral hepatitis A: detection of acute-phase immunoglobulin M anti-hepatitis A virus by radioimmunoassay.
- Specific immunoglobulin M response to hepatitis A virus determined by solid-phase radioimmunoassay.
- Etiological diagnosis of influenza A virus by enzymatic radioimmunoassay.
- Sites that bind polymerized albumin on hepatitis B surface antigen particles: detection by radioimmunoassay.
