Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir.
AUTOR(ES)
Hawkins, P R
RESUMO
Cylindrospermopsis raciborskii, a tropical blooming species of cyanobacterium (blue-green alga), was isolated from the domestic water supply reservoir on Palm Island, a continental island off the tropical northeast coast of Australia. This species, not previously known to be toxic, was shown to be severely hepatotoxic for mice. The 50% lethal dose at 24 h after injection was found to be 64 +/- 5 mg of freeze-dried culture per kg of mouse. The principal lesion produced was centrilobular to massive hepatocyte necrosis, but various degrees of injury were also seen in the kidneys, adrenal glands, lungs, and intestine. The possible implication of this finding in relation to an incident of hepatoenteritis in humans living on the island is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=238741Documentos Relacionados
- Coocorrência de Cylindrospermopsis raciborskii (Woloszynska) Seenaya & Subba Raju e Microcystis panniformis Komárek et al. no reservatório Mundaú, um ecossistema do semiárido brasileiro
- Dinâmica populacional de Cylindrospermopsis raciborskii (Woloszynska) Seenayya & Subba Raju, uma espécie tóxica de Cyanobacteria em reservatórios de abastecimento, SP, Brasil
- Cylindrospermopsis raciborskii (Woloszynska) Seenayya & Subba Raju(Cyanobacteria): variação semanal e relações com fatores ambientais em um reservatório eutrófico, São Paulo, SP, Brasil
- Efeitos de cepas de Cylindrospermopsis raciborskii(Woloszynska, 1912), Senayya & Subba Raju na mobilidade de Daphnia laevis (Cladocera, Daphniidae)
- Composição, variação temporal e espacial de cianobactérias, com ênfase na espécie cylindrospermopsis raciborskii (woloszynska) seenayya &subba raju no lago do Parque Professor Theobaldo Dick, Lajeado, Rio Grande do Sul, Brasil