Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum.

AUTOR(ES)

Mato, J M

RESUMO

Drops with different concentrations of 3':5'-cyclic AMP were deposited at various distances from small populations of Dictyostelium discoideum amoebae, and the distances over which 50% of the amoebae drops reacted positively were determined. The linear regression analysis of a bouble logarithmic plot of distance against concentration gives a straight line with a slope of 1/4.25, which value suggests that the amoebae respond to a spatial gradient of cyclic AMP concentration. The threshold value for the signal is 3.6 X 10(-9) M/mm with a sensitivity of measurement of about 1%. These findings are discussed in relation to our present knowledge of cyclic AMP receptors.

Documentos Relacionados

• Chromatin structure in the cellular slime mold Dictyostelium discoideum.
• Evidence for a Second Chemotactic System in the Cellular Slime Mold, Dictyostelium discoideum
• Protease activity during cell differentiation of the cellular slime mold Dictyostelium discoideum.
• Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum.
• The nucleotide sequence of 5S rRNA from a cellular slime mold Dictyostelium discoideum.