Simvastatin Inhibits Airway Hyperreactivity: Implications for the Mevalonate Pathway and Beyond

AUTOR(ES)
FONTE

American Thoracic Society

RESUMO

Rationale: Statin use has been linked to improved lung health in asthma and chronic obstructive pulmonary disease. We hypothesize that statins inhibit allergic airway inflammation and reduce airway hyperreactivity via a mevalonate-dependent mechanism.

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