Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215.
AUTOR(ES)
Searles, L L
RESUMO
Several P element insertion and deletion mutations near the 5' end of Drosophila melanogaster RpII215 have been examined by nucleotide sequencing. Two different sites of P element insertion, approximately 90 nucleotides apart, have been detected in this region of the gene. Therefore, including an additional site of P element insertion within the coding region, there are at least three distinct sites of P element insertion at RpII215. Both 5' sites are within a noncoding portion of transcribed sequences. The sequences of four revertants of one P element insertion mutation (D50) indicate that the P element is either precisely deleted or internally deleted to restore RpII215 activity. Partial internal deletions of the P element result in different RpII215 activity levels, which appear to depend on the specific sequences that remain after excision.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=367076Documentos Relacionados
- Antagonistic Interactions between Alleles of the Rpii215 Locus in Drosophila Melanogaster
- P-Element-Induced Recombination in Drosophila Melanogaster: Hybrid Element Insertion
- Insertion site preferences of the P transposable element in Drosophila melanogaster
- P-element-induced interallelic gene conversion of insertions and deletions in Drosophila melanogaster.
- Deletions in the 5' region of dystrophin and resulting phenotypes.
