Sorbic Hydroxamic Acid, an Antifungal Agent Effective over a Wide pH Range
AUTOR(ES)
Dudman, W. F.
RESUMO
Sorbic hydroxamic acid was prepared from sorbic acid by esterification and treatment with hydroxylamine (mp 133 to 135 C, pKa 8.8). Its ultraviolet spectrum in acid solution had a single absorption maximum at 262 mμ; in alkaline solution the maximal absorption shifted to 255 mμ and significant absorption appeared at 280 to 300 mμ. At concentrations of 0.1% (w/v), sorbic hydroxamic acid prevented the growth of Aspergillus niger, Penicillium notatum, Botrytis cinerea, Cladosporium herbarum, and a Rhizopus species in grape juice over the pH range 3.6 to 9.2, although sorbic acid was not effective at pH 5.7 and above.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1058003Documentos Relacionados
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