Specific immunological unresponsiveness to bacterial lipopolysaccharides develops in a cyclic manner.
AUTOR(ES)
Elkins, K L
RESUMO
Prior exposure (priming) of BALB/cByJ mice to a low dose of lipopolysaccharide derived from Escherichia coli 055 or Serratia marcescens, followed by immunization with an optimally immunogenic dose of the same lipopolysaccharide 2 to 30 days later, results in the expression of substantially reduced antibody responses. Such unresponsiveness, which is antigen specific, occurs in a cyclic manner with time after priming.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=313869Documentos Relacionados
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