Specificity of a Mycobacterium kansasii phenolic glycolipid (mycoside A) immunoserum.

AUTOR(ES)

Papa, F

RESUMO

The specificity of Mycobacterium kansasii anti-mycoside A antiserum prepared in rabbits injected with purified samples of the phenolic glycolipid was evaluated by an enzyme-linked immunosorbent assay. Chloroform-methanol extracts from representative strains of 23 mycobacterial species and 50 strains of M. kansasii showed that all strains of M. kansasii and the representative strain of M. gastri formed the antigen, whereas none of the remaining species (including M. leprae) formed it. Consequently, it was found that the antiserum was highly specific and useful for diagnostic purposes.

Documentos Relacionados

• Mycoside G, a Specific Glycolipid in Mycobacterium marinum (Balnei)
• Serological specificity of phenolic glycolipid I from Mycobacterium leprae and use in serodiagnosis of leprosy.
• BIOLOGICAL AND CHEMICAL STUDIES ON MYCOBACTERIA: Relationship of Colony Morphology to Mycoside Content for Mycobacterium kansasii and Mycobacterium fortuitum
• Isolation of the Mycobacterium leprae-specific glycolipid antigen, phenolic glycolipid-I, from formalin-fixed human lepromatous liver.
• A novel phenolic glycolipid from Mycobacterium leprae possibly involved in immunogenicity and pathogenicity.