Standardized method for evaluation of hand disinfection by surgical scrub formulations.

AUTOR(ES)

Crémieux, A

RESUMO

A standardized protocol for the evaluation of hand disinfection by surgical scrub formulations was applied to volunteers in a multicenter trial. Povidone iodine (PVI), chlorhexidine (CHX), and a nonmedicated soap (NMS) were tested. The scrubbing procedure involved three daily hand washings for five consecutive days; surviving bacteria were counted daily after being collected in a suitable neutralizing solution. Immediate efficacy (IE), cumulative efficacy (CE), and remanent effect (RE) were calculated by reference to the control hand. Statistical analyses of IE, CE, and RE showed significant differences among the three scrub formulations. IEs of PVI and CHX were equivalent and different from IE of NMS; CE and RE of CHX were higher than those of PVI and NMS. On the basis of the statistical analysis, the population size required for further studies aimed at detecting significant differences between surgical scrub formulations could be estimated.

Documentos Relacionados

• Polymers as carriers for rhizobial inoculant formulations.
• Extrusion/spheronization of pectin-based formulations. I. Screening of important factors
• Radioimmunoassay for octapeptide analogs of somatostatin: measurement of serum levels after administration of long-acting microcapsule formulations.
• Survival of anaerobic bacteria in various thioglycolate and chopped meat broth formulations.
• Comparative antibacterial activity of hexachlorophane in different formulations used for skin disinfection