Stimulation of aflatoxin B1 and T-2 toxin production by sorbic acid.
AUTOR(ES)
Gareis, M
RESUMO
Aspergillus flavus grown on yeast extract-sucrose medium produced higher amounts of aflatoxin B1 in the presence of 0.025% sorbic acid than without this chemical with a maximum at 17 days of incubation. Addition of 0.05 to 0.0125% sorbic acid stimulated T-2 toxin production of Fusarium acuminatum cultures grown on maize meal. The highest amounts of the mycotoxin were detected in 14-day-old cultures containing 0.025% sorbic acid. It is assumed that certain amounts of sorbic acid near the minimal inhibitory concentration reduce the activity of the tricarboxylic acid cycle; this may lead to an accumulation of acetyl coenzyme A, which is an essential intermediate in the biosynthesis of aflatoxin B1 and T-2 toxin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=239684Documentos Relacionados
- T-2 Toxin Production by Fusarium tricinctum on Solid Substrate 1
- Production of antibody against T-2 toxin.
- Quantitation of aflatoxin B1 and aflatoxin B1 antibody by an enzyme-linked immunosorbent microassay.
- Aflatoxin B1 dihydrodiol antibody: production and specificity.
- Surface Binding of Aflatoxin B1 by Lactic Acid Bacteria