Stimulation of Aryl Hydrocarbon Hydroxylase Induction in Cell Cultures by Interferon

AUTOR(ES)

Nebert, Daniel W.

RESUMO

In cell cultures previously treated with homologous interferon, the magnitude of antiviral activity and the degree of stimulation of aryl hydrocarbon hydroxylase induction appear to be directly related. In a highly purified mouse interferon preparation, the factor stimulating hydroxylase induction and the factor directing antiviral activity are inactivated by heating to 70 C or by treating with trypsin. Also, both activities demonstrate species specificity.

Documentos Relacionados

• Human Skin Aryl Hydrocarbon Hydroxylase: INDUCTION BY COAL TAR
• Expression of Aryl Hydrocarbon Hydroxylase Induction and Suppression of Tyrosine Aminotransferase Induction in Somatic-Cell Hybrids
• Induction of Aryl Hydrocarbon Hydroxylase in Human Pulmonary Alveolar Macrophages by Cigarette Smoking
• Comparison of Aryl Hydrocarbon Hydroxylase Induction in Cultured Blood Lymphocytes and Pulmonary Macrophages
• Aryl Hydrocarbon Hydroxylase Induction by Benzo[a]anthracene: Regulatory Gene Localized to the Distal Portion of Mouse Chromosome 17