Structural analysis of the ADHS electromorph of Drosophila melanogaster.

AUTOR(ES)

Fletcher, T S

RESUMO

Population geneticists have often determined the fitness differences that account for the dynamics of naturally occurring genetic polymorphisms. However, to understand causal aspects of evolutionary processes requires, in addition, investigation of the physiological and molecular structural differences underlying adaptively significant genetic polymorphisms. The characteristics of the alcohol dehydrogenase gene--enzyme system in Drosophila melanogaster make it well suited for this kind of study. Natural populations of this species are polymorphic for two electrophoretically detectable variants, ADHF and ADHS, of the enzyme. Structural studies reported here reveal that the two variants differ by (at least) a single amino acid replacement, threonine in ADHF for lysine in ADHS.

Documentos Relacionados

• Structural analysis of the three vitellogenin genes in Drosophila melanogaster.
• Structural genes on the Y chromosome of Drosophila melanogaster.
• Analysis of DNA structural patterns and sequence organization at the larval cuticle locus in Drosophila melanogaster.
• Molecular cloning and analysis of small optic lobes, a structural brain gene of Drosophila melanogaster.
• Structural organization of the Amy locus in seven strains of Drosophila melanogaster.