Structure and mobilization of an ampicillin and gentamicin resistance determinant.
AUTOR(ES)
Martin, C
RESUMO
A DNA segment originally found in an epidemic plasmid of Escherichia coli encoding an aminoglycoside-(3)-N-acetyltransferase gene (aacC5) and a TEM-type beta-lactamase gene was characterized. The two genes were adjacent and constituted a single transcriptional unit. In addition, these genes were simultaneously mobilized through the action of an insertion sequence related to IS26, IS140, and IS15-delta. This DNA segment is a composite transposon which has been called Tn2922.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174916Documentos Relacionados
- Allergic encephalomyelitis: the structure of encephalitogenic determinant.
- Mobilization of the gentamicin resistance gene in Enterococcus faecalis.
- Nucleotide sequence of the repressor gene of the TN10 tetracycline resistance determinant.
- Transcriptional analysis of the Staphylococcus aureus plasmid pI258 mercury resistance determinant.
- Development and use of cloning systems for Bacteroides fragilis: cloning of a plasmid-encoded clindamycin resistance determinant.