Structure and Polymorphism of the UL6 Portal Protein of Herpes Simplex Virus Type 1
AUTOR(ES)
Trus, Benes L.
FONTE
American Society for Microbiology
RESUMO
By electron microscopy and image analysis, we find that baculovirus-expressed UL6 is polymorphic, consisting of rings of 11-, 12-, 13-, and 14-fold symmetry. The 12-mer is likely to be the oligomer incorporated into procapsids: at a resolution of 16 Å, it has an axial channel, peripheral flanges, and fits snugly into a vacant vertex site. Its architecture resembles those of bacteriophage portal/connector proteins.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=525097Documentos Relacionados
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