Superiority of methylprednisolone over dexamethasone for induction of Pneumocystis carinii infection in rats.
AUTOR(ES)
Sukura, A
RESUMO
Because of difficulties in in vitro cultivation, the basic Pneumocystis carinii studies have been carried out on animal models, mainly on rodents immunosuppressed by corticosteroids. Commonly used dexamethasone and methylprednisolone procedures were evaluated. The intensity of infection in rats was statistically significantly higher after 9 weeks' immunosuppression with methylprednisolone than with dexamethasone.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=270323Documentos Relacionados
- Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats.
- Guanylhydrazones in therapy of Pneumocystis carinii pneumonia in immunosuppressed rats.
- Evidence for two genetic variants of Pneumocystis carinii coinfecting laboratory rats.
- Successful treatment with aerosolized pentamidine of Pneumocystis carinii pneumonia in rats.
- Antigenic differences associated with genetically distinct Pneumocystis carinii from rats.
