Synergistic In Vitro Antimalarial Activity of Omeprazole and Quinine
AUTOR(ES)
Skinner-Adams, T.
FONTE
American Society for Microbiology
RESUMO
Previous studies have shown that the proton pump inhibitor omeprazole has antimalarial activity in vitro. The interactions of omeprazole with commonly used antimalarial drugs were assessed in vitro. Omeprazole and quinine combinations were synergistic; however, chloroquine and omeprazole combinations were antagonistic. Artemisinin drugs had additive antimalarial activities with omeprazole.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89267Documentos Relacionados
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