Synthesis 12-Aryl or 12-Alkyl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives catalyzed by dodecatungstophosphoric acid
AUTOR(ES)
Wang, Hong-Juan, Ren, Xiao-Qian, Zhang, Yan-Yan, Zhang, Zhan-Hui
FONTE
Journal of the Brazilian Chemical Society
DATA DE PUBLICAÇÃO
2009
RESUMO
Um protocolo eficiente para a síntese de derivados de 12-aril ou 12-alquil-8,9,10,12-tetrahidro-benzo[a]xanten-11-one foi desenvolvido via reação de três componentes de aldeído, 2-naftol e 1,3-ciclohexadiona ou 5,5-dimetil-1,3-ciclohexadiona na presença de ácido 12-tungstofosfórico (H3PW12O40) sem o uso de solvente. A presente metodologia oferece muitas vantagens como altos rendimentos, procedimento simples, baixo custo, curto tempo de reação e condições brandas.
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