Synthesis of New Bis-Iminodihydrofurans

AUTOR(ES)

Tokmajyan, Gayane G., Karapetyan, Lusine V.

FONTE

J. Braz. Chem. Soc.

DATA DE PUBLICAÇÃO

2016-05

RESUMO

A new synthetic pathway to new bis-iminodihydrofurans is proposed, which involves the synthesis of N-substituted iminodihydrofurans from reaction of iminodihydrofurans with 2-cyanoacetohydrazide and their condensation with tertiary α-hydroxyketones. This sequence of reactions opens the new approach to the synthesis of novel polyheteroconjugated systems consisting from iminodihydrofuran rings. The methodology is simple, rapid and inexpensive affording high yields of the potentially bioactive products.

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