Synthesis of New Xanthenes Based on Lawsone and Coumarin via a Tandem Three-Component Reaction

AUTOR(ES)

Cardoso, Mariana F. C., Forezi, Luana S. M., Cavalcante, Victor G. S., Juliani, Cecília S. R., Resende, Jackson Antônio L. C., Rocha, David R. da, Silva, Fernando C. da, Ferreira, Vitor F.

FONTE

J. Braz. Chem. Soc.

DATA DE PUBLICAÇÃO

2017-10

RESUMO

The synthesis of several new xanthenes based on the 1,3-dicarbonyl scaffolds lawsone and coumarin was developed using tandem three-component reactions involving the reagents ortho-hydroxybenzaldehyde, as bifunctional reagent, and an appropriate thiol. These reactions generated two series of para- and ortho-naphthoxanthenes that are structurally related to α- and β-pyranaphthoquinones and one series of coumarin-xanthene derivatives.

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