Tandemly repeated tRNA pseudogenes in photobacterium.
AUTOR(ES)
Giroux, S
RESUMO
A region distal to three tRNA genes in Photobacterium phosphoreum, a Gram-negative eubacterium, unexpectedly contains a high number of repeated DNA segments that are closely related to the adjacent tRNAPro gene. The 5' to 3' order of this cluster is tRNAPro-tRNAHis-tRNAPro followed by eight tRNAPro-like structures interspersed by rho-independent terminators. The two tRNAPro genes, which are identical, and the tRNAHis gene have 86% and 87% positional identity, respectively, to their counterparts in the argT operon of Escherichia coli. The facts that these tRNA-like structures are not transcribed, in contrast to the tRNA retropseudogenes of eukaryotes, and that these structures are clustered near their progenitor suggest they are an unusual class of tRNA pseudogenes that arose by tandem duplication.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=282671Documentos Relacionados
- Small tandemly repeated DNA sequences of higher plants likely originate from a tRNA gene ancestor.
- Genes and pseudogenes in a reiterated rat tRNA gene cluster.
- The nucleotide sequence of a small metT tRNA operon from Photobacterium leiognathi.
- Interaction between human tRNA synthetases involves repeated sequence elements.
- Characterization of a rat tRNA gene cluster containing the genes for tRNAAsp, tRNAGly and tRNAGlu, and pseudogenes.