Temperature-Sensitive Variants of an Established Myoblast Line

AUTOR(ES)
RESUMO

Upon reaching confluency, mononucleated myoblasts fuse into multinucleated myotubes and concomitantly accumulate various characteristic muscle proteins, including myosin, actin, and several enzymes. We have approached the problem of determining the relationship between morphological and biochemical differentiation of muscle cells by isolating a series of temperature-sensitive clones from the established myoblast line, L6.

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