The adipocyte size contributes to the functional heterogeneity of white adipose tissue / O volume celular do adipócito contribui para a heterogeneidade funcional do tecido adiposo branco

AUTOR(ES)
DATA DE PUBLICAÇÃO

2010

RESUMO

The adipose tissue was considered to be a little active metabolic tissue, however, the most recent advances show that it plays an important function in the control of the energy homostasis. Based on this concept, this work aimed to characterize the morphology and metabolism of isolated adipocytes of three different depots, like: subcutaneous, periepididymal, retroperitoneal (SC, PE and RP) . The adipocytes of the different depots had been collected and submitted to morphologic analysis, metabolic assays and to analysis of the enzymes expressions involved on lipids and glucose metabolism. The results showed statistical significant difference on volume of the adipocytes among the three different depots (p<0, 05), high lipogenic capacity of RP adipocytes and higher expression of proteins involved in lipogenic patways of SC adipocytes (p<0, 05).

ASSUNTO(S)

gordura epididimal adipocyte epidymal fat retroperitoneal fat sub-cutaneous fat adipócito gordura sub cutânea metabolismo adipócito white adipose tissues adipocyte metabolism tecido adiposo branco gordura netro-peitoneal

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