The Chemotactic Activity of Various Sirenins and Analogues and the Uptake of Sirenin by the Sperm of Allomyces1

AUTOR(ES)

Machlis, Leonard

RESUMO

The enantiomorphs of sirenin and several analogues of sirenin were tested for their activity in attracting the sperm of Allomyces. Only l-sirenin was active. The uptake of sirenin by the sperm was measured from solutions containing l-sirenin in concentrations from 5 to 10,000 nm. Uptake from 5 and 100 nm followed first order kinetics. At higher concentrations the rate of uptake slowed down, and at the very highest ones it stopped after a few minutes. When sperm had taken up all the sirenin from a 5 nm solution, it took approximately 45 minutes for them to regain full responsiveness. After uptake of sirenin by sperm, none could be recovered from them.

Documentos Relacionados

• Effects of Analogs of the Fungal Sexual Pheromone Sirenin on Male Gamete Motility in Allomyces macrogynus1
• Factors Affecting the Stability and Accuracy of the Bioassay for the Sperm Attractant Sirenin 1
• Uptake of the glucose analogue 2-deoxyglucose by germinating mitospores of Allomyces macrogynus.
• Uptake of azithromycin by various cells and its intracellular activity under in vivo conditions.
• MICROBIOLOGICAL ACTIVITY OF ANALOGUES OF VITAMIN B12 BY THE CUP PLATE METHOD1