The contents of high-energy phosphates in different fibre types in skeletal muscles from rat, guinea-pig and man.
AUTOR(ES)
Edström, L
RESUMO
1. The contents of high-energy phosphates at rest have been measured in skeletal muscles with different fibre-type composition from rat, guinea-pig and man. All muscles studied biochemically have been characterized histochemically. 2. Fast-twitch muscles had a higher ATP/ADP ratio than slow-twitch muscles and, with the exception of the tongue in the rat, higher contents of ATP and phosphocreatine. 3. There was an inverse relationship between the content of phosphocreatine and the stainability for succinyl dehydrogenase, which is a marker enzyme for oxidative capacity. 4. The biochemical and histochemical data are discussed in relation to known morphological and functional properties of the different muscle-fibre types. It is concluded that fast-twitch fibres have a high ATP/ADP ratio favouring a fast acceleration of energy production. The content of phosphocreatine seems to be related to the glycolytic capacity but not to the contraction time. In addition to being an immediate energy source, phosphocreatine functions as a buffer against lactic acidosis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1197385Documentos Relacionados
- Effects of high-energy phosphates on carbachol-evoked cationic current in single smooth muscle cells from guinea-pig ileum.
- Effects of hypoxia on high-energy phosphagen content, energy metabolism and isometric force in guinea-pig taenia caeci.
- Oesophageal striated muscle arrangement and histochemical fibre types in guinea-pig, marmoset, macaque and man.
- Role of alpha-adrenoceptors in constrictor responses of rat, guinea-pig and rabbit small arteries to neural activation.
- Saturation in high-energy QCD