The effects of challenge on the humoral and cellular immune responses in pseudorabies vaccinated swine.
AUTOR(ES)
Alva-Valdes, R
RESUMO
The effects of challenge exposure on the humoral and cellular immune responses in pseudorabies vaccinated swine were studied in 84 barrows. The pigs were divided into seven groups and challenge exposed to a virulent strain of pseudorabies virus on months 1, 3, 5, 8, 10, 12 and 14 after vaccination. The pigs were vaccinated with commercial attenuated and inactivated pseudorabies virus vaccines. The protection conferred by vaccination was equally effective with both types of vaccines. The levels of cellular and humoral immunity after challenge exposure in pigs vaccinated with either type of vaccine were similar. The cell-mediated immune response can be effectively used for the early detection of pigs exposed to pseudorabies virus. Virus isolation attempts from the brain and spleen in most of the vaccinated pigs were unsuccessful.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1235974Documentos Relacionados
- Acute Effects of Pathogenic Simian-Human Immunodeficiency Virus Challenge on Vaccine-Induced Cellular and Humoral Immune Responses to Gag in Rhesus Macaques†
- Natural killing and antibody-dependent cellular cytotoxicity are independent immune functions in the Minnesota miniature swine.
- Pseudorabies virus nucleocapsid antigen for skin testing in swine.
- Indirect hemagglutination test for pseudorabies antibody detection in swine.
- Plasmid DNA encoding replicating foot-and-mouth disease virus genomes induces antiviral immune responses in swine.
