The estimation of recurrence risks in monogenic disorders using flanking marker loci.
AUTOR(ES)
Winter, R M
RESUMO
A method is presented of calculating recurrence risks at a disease locus where there is information from flanking marker loci. This method uses output from the computer programme LIPED. Information from carrier detection tests and mutation at the disease locus can be taken into account in certain pedigrees.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1049370Documentos Relacionados
- A computer programme to calculate risk in X linked disorders using multiple marker loci.
- Monogenic disorders.
- X linked neonatal centronuclear/myotubular myopathy: evidence for linkage to Xq28 DNA marker loci.
- Recurrence risks in mental retardation.
- Complexity in simplicity: monogenic disorders and complex cardiomyopathies
