The Gene yjfQ Encodes the Repressor of the yjfR-X Regulon (ula), Which Is Involved in l-Ascorbate Metabolism in Escherichia coli

AUTOR(ES)

Campos, Evangelina

FONTE

American Society for Microbiology

RESUMO

Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in l-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

Documentos Relacionados

• Regulation of Expression of the Divergent ulaG and ulaABCDEF Operons Involved in l-Ascorbate Dissimilation in Escherichia coli
• Utilization of l-Ascorbate by Escherichia coli K-12: Assignments of Functions to Products of the yjf-sga and yia-sgb Operons
• Conversion of Glucose to 2-Keto-l-Gulonate, an Intermediate in l-Ascorbate Synthesis, by a Recombinant Strain of Erwinia citreus
• Phenotypic revertant mutations of a new OmpR2 mutant (V203Q) of Escherichia coli lie in the envZ gene, which encodes the OmpR kinase.
• Characterization of a gene, glnL, the product of which is involved in the regulation of nitrogen utilization in Escherichia coli.