The genome of Mycobacterium leprae: a minimal mycobacterial gene set

AUTOR(ES)

Vissa, Varalakshmi D

FONTE

BioMed Central

RESUMO

Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis.

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