The in vivo pH of the extravascular space of the lung
AUTOR(ES)
Effros, Richard M.
RESUMO
The partition of 5,5-dimethyloxazolidine-2,4-dione (DMO) and of 11 amines between the vascular and extravascular spaces of the lung has been determined by the multiple indicator dilution technique. Four amines (nicotine, pentylamine, quinine, and benzylamine) were found to have pH-sensitive tissue to blood concentration ratios. Of these, tritiated nicotine appears to be the nost satisfactory indicator of tissue pH and values for the pH of the pulmonary extravascular space (pHe) have been calculated from the nicotine data. At an arterial pH (pHart) between 7.38 and 7.43 pHe averaged 6.69 ±0.07.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=297451Documentos Relacionados
- In vivo semen-associated pH neutralization of cervicovaginal secretions.
- In vivo myocardial cell pH in the dog. Response to ischemia and infusion of alkali.
- Developmental adaptations in cytosolic phosphate content and pH regulation in the sheep heart in vivo.
- Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.
- Effect of external pH perturbations on in vivo protein synthesis by the acidophilic bacterium Thiobacillus ferrooxidans.