The Interleukin-17 Gene of Herpesvirus Saimiri

AUTOR(ES)

Knappe, Andrea

FONTE

American Society for Microbiology

RESUMO

In comparison to wild-type herpesvirus saimiri, viral interleukin-17 gene knockout mutants have unaltered behavior regarding viral replication, T-cell transformation in vitro, and pathogenicity in cottontop tamarins. Thus, this gene is not required for T-cell lymphoma induction but may contribute to apathogenic viral persistence in the natural host, the squirrel monkey.

Documentos Relacionados

• Interleukin-17 and systemic lupus erythematosus: current concepts
• Inhibition of Interleukin-17 Prevents the Development of Arthritis in Vaccinated Mice Challenged with Borrelia burgdorferi
• Organization of the thymidylate synthase gene of herpesvirus saimiri.
• Association of Interleukin-17 polymorphism (-197G/A) in chronic and localized aggressive periodontitis
• Systemic and Local Interleukin-17 and Linked Cytokines Associated with Sjögren’s Syndrome Immunopathogenesis